The Microscopy Knowledge Portal

The surgical team at Retina Clinic in São Paulo, Brazil, has been using microscope-integrated intraoperative OCT for the past year. In their white…

Leica Microsystems’ Nano workflow combines dynamic data with the best possible sample fixation (EM ICE 70) by high pressure freezing. However, good…

In this White Paper, Dr. Rachid Tahiri shares his personal experience with the Leica EnFocus intraoperative OCT, the valuable features supporting…

This article discusses the reasons why paper-based documentation and reporting makes visual microscope inspection of medical devices inefficient and…

In life science research, live cell imaging is an indispensable tool to visualize cells in a state as in vivo as possible. This E-book reviews a wide…

This publication is a compilation of appropriate workflows for the most frequently used sample preparation methods, like Correlative Methodologies,…

Today, ion beam milling is one of the most widely-used methods for preparing samples for electron microscopy. Download this 76-pages booklet today and…

This article discusses how manual visual inspection, which is prevalent in the medical device industry, can lead to inconsistent results. It also…

The EM ICE High Pressure Freezer was developed with a unique freezing principle and uses only a single pressurization and cooling liquid: liquified…

In this article, how cryo light microscopy and, in particular cryo confocal microscopy, is used to improve the reliability of cryo EM workflows is…

Dr Barbara Parolini is one of the pioneers in the use of intraoperative OCT in eye surgery. Since 2016, she has gained a lot of clinical experience…

Deconvolution is a computational method used to restore the image of the object that is corrupted by the point spread function (PSF) along with…

The analysis of fired cartridges for primer cup morphology and flattening and firing pin impression (crater) depth using topographic data is discussed…

Gene augmentation therapy is a method of ocular gene transfer for autosomal recessive or X-linked retinal dystrophies when there is insufficient…

The rating of non-metallic inclusions (NMIs) to determine steel quality is critical for many industrial applications. For an efficient and…

Viral entry into the host cell requires the coordination of many cellular and viral proteins in a precise order. Modern microscopy techniques are now…

Many software packages include background subtraction algorithms to enhance the contrast of features in the image by reducing background noise. The…

Rapid, accurate, and reliable rating of non-metallic inclusions (NMIs) is instrumental for the determination of steel quality. This article describes…